ABSTRACT
By linking differential gene expression to the chromosomal localization of genes, one can investigate microarray data for characteristic patterns of expression phenomena involving sizeable parts of specific chromosomes. We have implemented a statistical approach for identifying significantly differentially expressed chromosome regions. We demonstrate the applicability of the approach on a publicly available data set on acute lymphocytic leukemia.
The software is implemented as a R / Bioconductor package. You can download it here.
You also find information about the developers and an exhaustive documentation.
Matthias Heinig Last modified: Mon Nov 29 12:24:47 CET 2004